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Alignment and mapping methodology influence transcript abundance estimation

BACKGROUND: The accuracy of transcript quantification using RNA-seq data depends on many factors, such as the choice of alignment or mapping method and the quantification model being adopted. While the choice of quantification model has been shown to be important, considerably less attention has bee...

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Detalles Bibliográficos
Autores principales: Srivastava, Avi, Malik, Laraib, Sarkar, Hirak, Zakeri, Mohsen, Almodaresi, Fatemeh, Soneson, Charlotte, Love, Michael I., Kingsford, Carl, Patro, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487471/
https://www.ncbi.nlm.nih.gov/pubmed/32894187
http://dx.doi.org/10.1186/s13059-020-02151-8