Mice defective in interferon signaling help distinguish between primary and secondary pathological pathways in a mouse model of neuronal forms of Gaucher disease

BACKGROUND: The type 1 interferon (IFN) response is part of the innate immune response and best known for its role in viral and bacterial infection. However, this pathway is also induced in sterile inflammation such as that which occurs in a number of neurodegenerative diseases, including neuronopat...

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Detalles Bibliográficos
Autores principales: Vardi, Ayelet, Ben-Dor, Shifra, Cho, Soo Min, Kalinke, Ulrich, Spanier, Julia, Futerman, Anthony H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487497/
https://www.ncbi.nlm.nih.gov/pubmed/32892753
http://dx.doi.org/10.1186/s12974-020-01934-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487497/
https://www.ncbi.nlm.nih.gov/pubmed/32892753
http://dx.doi.org/10.1186/s12974-020-01934-x

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