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The crosstalk of ABCA1 and ANXA1: a potential mechanism for protection against atherosclerosis

Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by med...

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Detalles Bibliográficos
Autores principales: Shen, Xin, Zhang, Shun, Guo, Zhu, Xing, Dongming, Chen, Wujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487582/
https://www.ncbi.nlm.nih.gov/pubmed/32894039
http://dx.doi.org/10.1186/s10020-020-00213-y