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Lgr5 and stem/progenitor gene expression in gastric/gastroesophageal junction carcinoma – significance of potentially retained stemness

BACKGROUND: Gastric/gastroesophageal junction (GEJ) adenocarcinomas are heterogeneous, comprising four molecularly distinct subtypes, namely EBV-positive, microsatellite instability (MSI), chromosomal instability (CIN) and genomically stable (GS) subtypes, and a part of this heterogeneity may hypoth...

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Detalles Bibliográficos
Autores principales: Yoon, Ju-Yoon, Brezden-Masley, Christine, Streutker, Catherine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487651/
https://www.ncbi.nlm.nih.gov/pubmed/32894084
http://dx.doi.org/10.1186/s12885-020-07362-7