Aneuploidy-induced proteotoxic stress can be effectively tolerated without dosage compensation, genetic mutations, or stress responses

BACKGROUND: The protein homeostasis (proteostasis) network maintains balanced protein synthesis, folding, transport, and degradation within a cell. Failure to maintain proteostasis is associated with aging and disease, leading to concerted efforts to study how the network responds to various proteot...

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Detalles Bibliográficos
Autores principales: Larrimore, Katherine E., Barattin-Voynova, Natalia S., Reid, David W., Ng, Davis T. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487686/
https://www.ncbi.nlm.nih.gov/pubmed/32900371
http://dx.doi.org/10.1186/s12915-020-00852-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487686/
https://www.ncbi.nlm.nih.gov/pubmed/32900371
http://dx.doi.org/10.1186/s12915-020-00852-x

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