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Discrete dynamic network modeling of oncogenic signaling: Mechanistic insights for personalized treatment of cancer
Targeted drugs disrupting proteins that are dysregulated in cancer have emerged as promising treatments because of their specificity to cancer cell aberrations and thus their improved side effect profile. However, their success remains limited, largely due to existing or emergent therapy resistance....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Ltd
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487767/ https://www.ncbi.nlm.nih.gov/pubmed/32954058 http://dx.doi.org/10.1016/j.coisb.2018.02.002 |