Naive Pluripotent Stem Cells Exhibit Phenotypic Variability that Is Driven by Genetic Variation

Variability among pluripotent stem cell (PSC) lines is a prevailing issue that hampers not only experimental reproducibility but also large-scale applications and personalized cell-based therapy. This variability could result from epigenetic and genetic factors that influence stem cell behavior. Nai...

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Detalles Bibliográficos
Autores principales: Ortmann, Daniel, Brown, Stephanie, Czechanski, Anne, Aydin, Selcan, Muraro, Daniele, Huang, Yuanhua, Tomaz, Rute A., Osnato, Anna, Canu, Giovanni, Wesley, Brandon T., Skelly, Daniel A., Stegle, Oliver, Choi, Ted, Churchill, Gary A., Baker, Christopher L., Rugg-Gunn, Peter J., Munger, Steven C., Reinholdt, Laura G., Vallier, Ludovic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487768/
https://www.ncbi.nlm.nih.gov/pubmed/32795399
http://dx.doi.org/10.1016/j.stem.2020.07.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487768/
https://www.ncbi.nlm.nih.gov/pubmed/32795399
http://dx.doi.org/10.1016/j.stem.2020.07.019

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