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Associations of maternal early-pregnancy blood glucose and insulin concentrations with DNA methylation in newborns

BACKGROUND: Intrauterine exposure to a disturbed maternal glucose metabolism is associated with adverse offspring outcomes. DNA methylation is a potential mechanism underlying these associations. We examined whether maternal early-pregnancy glucose and insulin concentrations are associated with newb...

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Detalles Bibliográficos
Autores principales: Geurtsen, Madelon L., Jaddoe, Vincent W. V., Gaillard, Romy, Felix, Janine F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487846/
https://www.ncbi.nlm.nih.gov/pubmed/32894192
http://dx.doi.org/10.1186/s13148-020-00924-3