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Long-term efficacy and tolerability of lemborexant compared with placebo in adults with insomnia disorder: results from the phase 3 randomized clinical trial SUNRISE 2

STUDY OBJECTIVES: To assess long-term efficacy and safety of lemborexant (LEM), a novel dual orexin receptor antagonist, versus placebo in adults with insomnia disorder. METHODS: This was a 12-month, global, multicenter, randomized, double-blind, parallel-group phase 3 study comprising a 6-month pla...

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Detalles Bibliográficos
Autores principales: Kärppä, Mikko, Yardley, Jane, Pinner, Kate, Filippov, Gleb, Zammit, Gary, Moline, Margaret, Perdomo, Carlos, Inoue, Yuichi, Ishikawa, Kohei, Kubota, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487867/
https://www.ncbi.nlm.nih.gov/pubmed/32585700
http://dx.doi.org/10.1093/sleep/zsaa123