Cargando…

XIST lost induces ovarian cancer stem cells to acquire taxol resistance via a KMT2C-dependent way

BACKGROUND/AIMS: The expression levels of long non-coding RNA XIST are significantly associated with paclitaxel (Pac) sensitivity in ovarian cancer, but the mechanism of action remains unclear. Therefore, this experimental design was based on lncRNA XIST analysis to regulate the effect of XIST on th...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Ruili, Zhu, Lijuan, Zhang, Yali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487955/
https://www.ncbi.nlm.nih.gov/pubmed/32943985
http://dx.doi.org/10.1186/s12935-020-01500-8