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A novel mouse model expressing human forms for complement receptors CR1 and CR2

BACKGROUND: The complement cascade is increasingly implicated in development of a variety of diseases with strong immune contributions such as Alzheimer’s disease and Systemic Lupus Erythematosus. Mouse models have been used to determine function of central components of the complement cascade such...

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Detalles Bibliográficos
Autores principales: Jackson, Harriet M., Foley, Kate E., O’Rourke, Rita, Stearns, Timothy M., Fathalla, Dina, Morgan, B. Paul, Howell, Gareth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487969/
https://www.ncbi.nlm.nih.gov/pubmed/32907542
http://dx.doi.org/10.1186/s12863-020-00893-9