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A novel mouse model expressing human forms for complement receptors CR1 and CR2
BACKGROUND: The complement cascade is increasingly implicated in development of a variety of diseases with strong immune contributions such as Alzheimer’s disease and Systemic Lupus Erythematosus. Mouse models have been used to determine function of central components of the complement cascade such...
Autores principales: | Jackson, Harriet M., Foley, Kate E., O’Rourke, Rita, Stearns, Timothy M., Fathalla, Dina, Morgan, B. Paul, Howell, Gareth R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487969/ https://www.ncbi.nlm.nih.gov/pubmed/32907542 http://dx.doi.org/10.1186/s12863-020-00893-9 |
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