NMDA receptor-mediated CaMKII/ERK activation contributes to renal fibrosis

BACKGROUND: This study aimed to understand the mechanistic role of N-methyl-D-aspartate receptor (NMDAR) in acute fibrogenesis using models of in vivo ureter obstruction and in vitro TGF-β administration. METHODS: Acute renal fibrosis (RF) was induced in mice by unilateral ureteral obstruction (UUO)...

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Detalles Bibliográficos
Autores principales: Zhou, Jingyi, Liu, Shuaihui, Guo, Luying, Wang, Rending, Chen, Jianghua, Shen, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488001/
https://www.ncbi.nlm.nih.gov/pubmed/32907546
http://dx.doi.org/10.1186/s12882-020-02050-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488001/
https://www.ncbi.nlm.nih.gov/pubmed/32907546
http://dx.doi.org/10.1186/s12882-020-02050-x

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