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GLaMST: grow lineages along minimum spanning tree for b cell receptor sequencing data
BACKGROUND: B cell affinity maturation enables B cells to generate high-affinity antibodies. This process involves somatic hypermutation of B cell immunoglobulin receptor (BCR) genes and selection by their ability to bind antigens. Lineage trees are used to describe this microevolution of B cell imm...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488003/ https://www.ncbi.nlm.nih.gov/pubmed/32900378 http://dx.doi.org/10.1186/s12864-020-06936-w |