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GLaMST: grow lineages along minimum spanning tree for b cell receptor sequencing data

BACKGROUND: B cell affinity maturation enables B cells to generate high-affinity antibodies. This process involves somatic hypermutation of B cell immunoglobulin receptor (BCR) genes and selection by their ability to bind antigens. Lineage trees are used to describe this microevolution of B cell imm...

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Detalles Bibliográficos
Autores principales: Yang, Xingyu, Tipton, Christopher M., Woodruff, Matthew C., Zhou, Enlu, Lee, F. Eun-Hyung, Sanz, Inãki, Qiu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488003/
https://www.ncbi.nlm.nih.gov/pubmed/32900378
http://dx.doi.org/10.1186/s12864-020-06936-w