Cargando…
GLaMST: grow lineages along minimum spanning tree for b cell receptor sequencing data
BACKGROUND: B cell affinity maturation enables B cells to generate high-affinity antibodies. This process involves somatic hypermutation of B cell immunoglobulin receptor (BCR) genes and selection by their ability to bind antigens. Lineage trees are used to describe this microevolution of B cell imm...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488003/ https://www.ncbi.nlm.nih.gov/pubmed/32900378 http://dx.doi.org/10.1186/s12864-020-06936-w |