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Targeting NEK2 impairs oncogenesis and radioresistance via inhibiting the Wnt1/β-catenin signaling pathway in cervical cancer
BACKGROUND: NEK2, a serine/threonine kinase involved in mitosis, has been found to function in chromosome instability, tumor progression and metastasis, but its role in cervical cancer radioresistance remains unknown. METHODS: We detected the protein levels of NEK2 in cervical carcinoma tissues and...
Autores principales: | Xu, Tie, Zeng, Yulan, Shi, Linli, Yang, Qin, Chen, Yeshan, Wu, Gang, Li, Guiling, Xu, Shuangbing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488040/ https://www.ncbi.nlm.nih.gov/pubmed/32907622 http://dx.doi.org/10.1186/s13046-020-01659-y |
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