STARR-seq identifies active, chromatin-masked, and dormant enhancers in pluripotent mouse embryonic stem cells

BACKGROUND: Enhancers are distal regulators of gene expression that shape cell identity and control cell fate transitions. In mouse embryonic stem cells (mESCs), the pluripotency network is maintained by the function of a complex network of enhancers, that are drastically altered upon differentiatio...

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Detalles Bibliográficos
Autores principales: Peng, Tianran, Zhai, Yanan, Atlasi, Yaser, ter Huurne, Menno, Marks, Hendrik, Stunnenberg, Hendrik G., Megchelenbrink, Wout
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488044/
https://www.ncbi.nlm.nih.gov/pubmed/32912294
http://dx.doi.org/10.1186/s13059-020-02156-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488044/
https://www.ncbi.nlm.nih.gov/pubmed/32912294
http://dx.doi.org/10.1186/s13059-020-02156-3

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