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Human MDSCs derived from the bone marrow maintain their functional ability but have a reduced frequency of induction in the elderly compared to pediatric donors

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immunosuppressive cells developing from myeloid progenitors, which are enriched in pathological conditions such as cancer, and are known to inhibit the functions of effector T cells. During aging, several changes occur both a...

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Detalles Bibliográficos
Autores principales:	Magri, Sara, Masetto, Elena, Solito, Samantha, Francescato, Samuela, Belluzzi, Elisa, Pozzuoli, Assunta, Berizzi, Antonio, Ruggieri, Pietro, Mandruzzato, Susanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488050/ https://www.ncbi.nlm.nih.gov/pubmed/32944054 http://dx.doi.org/10.1186/s12979-020-00199-5

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