Caspase-1 has a critical role in blood-brain barrier injury and its inhibition contributes to multifaceted repair

BACKGROUND: Excessive inflammation might activate and injure the blood-brain barrier (BBB), a common feature of many central nervous system (CNS) disorders. We previously developed an in vitro BBB injury model in which the organophosphate paraoxon (PX) affects the BBB endothelium by attenuating junc...

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Detalles Bibliográficos
Autores principales: Israelov, Hila, Ravid, Orly, Atrakchi, Dana, Rand, Daniel, Elhaik, Shirin, Bresler, Yael, Twitto-Greenberg, Rachel, Omesi, Liora, Liraz-Zaltsman, Sigal, Gosselet, Fabien, Schnaider Beeri, Michal, Cooper, Itzik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488082/
https://www.ncbi.nlm.nih.gov/pubmed/32907600
http://dx.doi.org/10.1186/s12974-020-01927-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488082/
https://www.ncbi.nlm.nih.gov/pubmed/32907600
http://dx.doi.org/10.1186/s12974-020-01927-w

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