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A three-arm, multicenter, open-label randomized controlled trial of hydroxychloroquine and low-dose prednisone to treat recurrent pregnancy loss in women with undifferentiated connective tissue diseases: protocol for the Immunosuppressant regimens for LIving FEtuses (ILIFE) trial

BACKGROUND: Undifferentiated connective tissue disease (UCTD) is known to induce adverse pregnancy outcomes and even recurrent spontaneous abortion (RSA) by placental vascular damage and inflammation activation. Anticoagulation can prevent pregnancy morbidities. However, it is unknown whether the ad...

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Detalles Bibliográficos
Autores principales: Yang, Shaoying, Ni, Ruoning, Lu, Yikang, Wang, Suli, Xie, Feng, Zhang, Chunyan, Lu, Liangjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488113/
https://www.ncbi.nlm.nih.gov/pubmed/32907619
http://dx.doi.org/10.1186/s13063-020-04716-1