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Phosphodiesterase 5 inhibitor sildenafil in patients with heart failure with preserved ejection fraction and combined pre- and postcapillary pulmonary hypertension: a randomized open-label pilot study

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is frequently complicated by pulmonary hypertension (PH). A pulmonary vascular contribution could be considered as a substantial therapeutic target in HFpEF and PH and combined pre- and postcapillary PH (Cpc-PH). METHODS: We enrolled...

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Detalles Bibliográficos
Autores principales: Belyavskiy, Evgeny, Ovchinnikov, Artem, Potekhina, Alexandra, Ageev, Fail, Edelmann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488149/
https://www.ncbi.nlm.nih.gov/pubmed/32912157
http://dx.doi.org/10.1186/s12872-020-01671-2