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LOXL1 modulates the malignant progression of colorectal cancer by inhibiting the transcriptional activity of YAP

BACKGROUND: LOX-like 1 (LOXL1) is a lysyl oxidase, and emerging evidence has revealed its effect on malignant cancer progression. However, its role in colorectal cancer (CRC) and the underlying molecular mechanisms have not yet been elucidated. METHODS: LOXL1 expression in colorectal cancer was dete...

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Detalles Bibliográficos
Autores principales: Hu, Lin, Wang, Jing, Wang, Yunliang, Wu, Linpeng, Wu, Chao, Mao, Bo, Maruthi Prasad, E., Wang, Yuhong, Chin, Y. Eugene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488294/
https://www.ncbi.nlm.nih.gov/pubmed/32912229
http://dx.doi.org/10.1186/s12964-020-00639-1