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Miltirone induces cell death in hepatocellular carcinoma cell through GSDME-dependent pyroptosis

Pyroptosis is a form of programmed cell death, and recently described as a new molecular mechanism of chemotherapy drugs in the treatment of tumors. Miltirone, a derivative of phenanthrene-quinone isolated from the root of Salvia miltiorrhiza Bunge, has been shown to possess anti-cancer activities....

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Detalles Bibliográficos
Autores principales: Zhang, Xiaowei, Zhang, Ping, An, Lin, Sun, Ningyuan, Peng, Liying, Tang, Weiwei, Ma, Dingyuan, Chen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488361/
https://www.ncbi.nlm.nih.gov/pubmed/32963939
http://dx.doi.org/10.1016/j.apsb.2020.06.015