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Elevated expression of RUNX3 co-expressing with EZH2 in esophageal cancer patients from India

BACKGROUND: Runt related transcription factor3 (RUNX3) is considered as a tumor suppressor gene (TSG) that functions through the TGF-β dependent apoptosis. Promoter methylation of the CpG islands of RUNX3 and overexpression of enhancer of zeste homolog 2 (EZH2) has been suggested to downregulate RUN...

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Detalles Bibliográficos
Autores principales: Rehman, Asad Ur, Iqbal, Mohammad Askandar, Sattar, Real Sumayya Abdul, Saikia, Snigdha, Kashif, Mohammad, Ali, Wasif Mohammad, Medhi, Subhash, Saluja, Sundeep Singh, Husain, Syed Akhtar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488393/
https://www.ncbi.nlm.nih.gov/pubmed/32943993
http://dx.doi.org/10.1186/s12935-020-01534-y