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Pharmacokinetics of anticoagulant edoxaban in overdose in a Japanese patient transported to hospital

BACKGROUND: The anticoagulant edoxaban is used clinically at doses of 30–60 mg/day; however, we experienced a patient who had taken an overdose of edoxaban of 750 mg. We investigated the pharmacokinetics of edoxaban in this patient by using liquid chromatography–tandem spectrometry to estimate the f...

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Detalles Bibliográficos
Autores principales: Adachi, Koichiro, Tuchiya, Jumpei, Beppu, Satoru, Nishiyama, Kei, Shimizu, Makiko, Yamazaki, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488402/
https://www.ncbi.nlm.nih.gov/pubmed/32944263
http://dx.doi.org/10.1186/s40780-020-00176-6