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T2 heterogeneity: a novel marker of microstructural integrity associated with cognitive decline in people with mild cognitive impairment
BACKGROUND: Early Alzheimer’s disease (AD) diagnosis is vital for development of disease-modifying therapies. Prior to significant brain tissue atrophy, several microstructural changes take place as a result of Alzheimer’s pathology. These include deposition of amyloid, tau and iron, as well as alte...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488446/ https://www.ncbi.nlm.nih.gov/pubmed/32912337 http://dx.doi.org/10.1186/s13195-020-00672-9 |