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Reduced mitochondrial D-loop methylation levels in sporadic amyotrophic lateral sclerosis
BACKGROUND: Mitochondrial dysregulation and aberrant epigenetic mechanisms have been frequently reported in neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), and several researchers suggested that epigenetic dysregulation in mitochondrial DNA (mtDNA) could contribute to the...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488473/ https://www.ncbi.nlm.nih.gov/pubmed/32917270 http://dx.doi.org/10.1186/s13148-020-00933-2 |