Reduced mitochondrial D-loop methylation levels in sporadic amyotrophic lateral sclerosis

BACKGROUND: Mitochondrial dysregulation and aberrant epigenetic mechanisms have been frequently reported in neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), and several researchers suggested that epigenetic dysregulation in mitochondrial DNA (mtDNA) could contribute to the...

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Detalles Bibliográficos
Autores principales: Stoccoro, Andrea, Smith, Adam R., Mosca, Lorena, Marocchi, Alessandro, Gerardi, Francesca, Lunetta, Christian, Cereda, Cristina, Gagliardi, Stella, Lunnon, Katie, Migliore, Lucia, Coppedè, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488473/
https://www.ncbi.nlm.nih.gov/pubmed/32917270
http://dx.doi.org/10.1186/s13148-020-00933-2

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