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Disruption of zinc transporter ZnT3 transcriptional activity and synaptic vesicular zinc in the brain of Huntington’s disease transgenic mouse

BACKGROUND: Huntington’s disease (HD) is a neurodegenerative disease that involves a complex combination of psychiatric, cognitive and motor impairments. Synaptic dysfunction has been implicated in HD pathogenesis. However, the mechanisms have not been clearly delineated. Synaptic vesicular zinc is...

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Detalles Bibliográficos
Autores principales: Niu, Li, Li, Li, Yang, Shiming, Wang, Weixi, Ye, Cuifang, Li, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488477/
https://www.ncbi.nlm.nih.gov/pubmed/32944220
http://dx.doi.org/10.1186/s13578-020-00459-3