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A facile and scalable in production non-viral gene engineered mesenchymal stem cells for effective suppression of temozolomide-resistant (TMZR) glioblastoma growth

BACKGROUND: Mesenchymal stem cells (MSCs) serve as an attractive vehicle for cell-directed enzyme prodrug therapy (CDEPT) due to their unique tumour-nesting ability. Such approach holds high therapeutic potential for treating solid tumours including glioblastoma multiforme (GBM), a devastating disea...

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Detalles Bibliográficos
Autores principales: Tu, Geraldine Xue En, Ho, Yoon Khei, Ng, Zhi Xu, Teo, Ke Jia, Yeo, Tseng Tsai, Too, Heng-Phon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488524/
https://www.ncbi.nlm.nih.gov/pubmed/32917269
http://dx.doi.org/10.1186/s13287-020-01899-x