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Hepatocyte-like cells derived from human induced pluripotent stem cells using small molecules: implications of a transcriptomic study

BACKGROUND: Hepatocyte-like cells (HLCs) derived from human induced pluripotent stem cells (iPSCs) hold great promise in toxicological applications as well as in regenerative medicine. Previous efforts on hepatocyte differentiation have mostly relied on the use of growth factors (GFs) to recapitulat...

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Detalles Bibliográficos
Autores principales: Gao, Xiugong, Li, Rong, Cahan, Patrick, Zhao, Yang, Yourick, Jeffrey J., Sprando, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488531/
https://www.ncbi.nlm.nih.gov/pubmed/32917265
http://dx.doi.org/10.1186/s13287-020-01914-1