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Hepatocyte-like cells derived from human induced pluripotent stem cells using small molecules: implications of a transcriptomic study
BACKGROUND: Hepatocyte-like cells (HLCs) derived from human induced pluripotent stem cells (iPSCs) hold great promise in toxicological applications as well as in regenerative medicine. Previous efforts on hepatocyte differentiation have mostly relied on the use of growth factors (GFs) to recapitulat...
Autores principales: | Gao, Xiugong, Li, Rong, Cahan, Patrick, Zhao, Yang, Yourick, Jeffrey J., Sprando, Robert L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488531/ https://www.ncbi.nlm.nih.gov/pubmed/32917265 http://dx.doi.org/10.1186/s13287-020-01914-1 |
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