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Estimating the Binding of Sars-CoV-2 Peptides to HLA Class I in Human Subpopulations Using Artificial Neural Networks

Epidemiological studies show that SARS-CoV-2 infection leads to severe symptoms only in a fraction of patients, but the determinants of individual susceptibility to the virus are still unknown. The major histocompatibility complex (MHC) class I exposes viral peptides in all nucleated cells and is in...

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Detalles Bibliográficos
Autores principales: La Porta, Caterina A.M., Zapperi, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488596/
https://www.ncbi.nlm.nih.gov/pubmed/32916095
http://dx.doi.org/10.1016/j.cels.2020.08.011