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HKDC1 promotes the tumorigenesis and glycolysis in lung adenocarcinoma via regulating AMPK/mTOR signaling pathway

BACKGROUND: Hexokinase domain component 1 (HKDC1) plays an oncogenic role in certain types of cancer, such as lymphoma, liver cancer, and breast cancer. Previous bioinformatics study revealed that HKDC1 was significantly upregulated in lung adenocarcinoma (LUAD). However, its biological functions an...

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Detalles Bibliográficos
Autores principales: Wang, Xinyu, Shi, Bowen, Zhao, Yue, Lu, Qijue, Fei, Xiang, Lu, Chaojing, Li, Chunguang, Chen, Hezhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488676/
https://www.ncbi.nlm.nih.gov/pubmed/32943998
http://dx.doi.org/10.1186/s12935-020-01539-7