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Presence of heat shock protein 47-positive fibroblasts in cancer stroma is associated with increased risk of postoperative recurrence in patients with lung cancer

BACKGROUND: Heat shock protein 47 (HSP47), a collagen-binding protein, has a specific role in the intracellular processing of procollagen production. HSP47 expression is associated with cancer growth and metastasis in several types of cancers. However, none of the studies have assessed whether HSP47...

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Detalles Bibliográficos
Autores principales: Miyamura, Takuto, Sakamoto, Noriho, Ishida, Kaori, Kakugawa, Tomoyuki, Taniguchi, Hirokazu, Akiyama, Yoshiko, Okuno, Daisuke, Hara, Atsuko, Kido, Takashi, Ishimoto, Hiroshi, Miyazaki, Takuro, Matsumoto, Keitaro, Tsuchiya, Tomoshi, Yamaguchi, Hiroyuki, Miyazaki, Taiga, Obase, Yasushi, Ishimatsu, Yuji, Nagayasu, Takeshi, Mukae, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488681/
https://www.ncbi.nlm.nih.gov/pubmed/32928242
http://dx.doi.org/10.1186/s12931-020-01490-1