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Platelet adhesion and aggregate formation controlled by immobilised and soluble VWF

BACKGROUND: It has been demonstrated that von Willebrand factor (VWF) mediated platelet-endothelium and platelet-platelet interactions are shear dependent. The VWF’s mobility under dynamic conditions (e.g. flow) is pivotal to platelet adhesion and VWF-mediated aggregate formation in the cascade of V...

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Detalles Bibliográficos
Autores principales: Schneider, Matthias F., Fallah, Mohammad A., Mess, Christian, Obser, Tobias, Schneppenheim, Reinhard, Alexander-Katz, Alfredo, Schneider, Stefan W., Huck, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488753/
https://www.ncbi.nlm.nih.gov/pubmed/32917131
http://dx.doi.org/10.1186/s12860-020-00309-7