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LAG-3: from molecular functions to clinical applications

To prevent the destruction of tissues owing to excessive and/or inappropriate immune responses, immune cells are under strict check by various regulatory mechanisms at multiple points. Inhibitory coreceptors, including programmed cell death 1 (PD-1) and cytotoxic T lymphocyte antigen 4 (CTLA-4), ser...

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Detalles Bibliográficos
Autores principales: Maruhashi, Takumi, Sugiura, Daisuke, Okazaki, Il-mi, Okazaki, Taku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488795/
https://www.ncbi.nlm.nih.gov/pubmed/32929051
http://dx.doi.org/10.1136/jitc-2020-001014