Thymoquinone and Difluoromethylornithine (DFMO) Synergistically Induce Apoptosis of Human Acute T Lymphoblastic Leukemia Jurkat Cells Through the Modulation of Epigenetic Pathways

Thymoquinone (TQ), a natural anticancer agent exerts cytotoxic effects on several tumors by targeting multiple pathways, including apoptosis. Difluoromethylornithine (DFMO), an irreversible inhibitor of the ornithine decarboxylase (ODC) enzyme, has shown promising inhibitory activities in many cance...

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Detalles Bibliográficos
Autores principales: Alhosin, Mahmoud, Razvi, Syed Shoeb I., Sheikh, Ryan A., Khan, Jalaluddin A., Zamzami, Mazin A., Choudhry, Hani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488875/
https://www.ncbi.nlm.nih.gov/pubmed/32912061
http://dx.doi.org/10.1177/1533033820947489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488875/
https://www.ncbi.nlm.nih.gov/pubmed/32912061
http://dx.doi.org/10.1177/1533033820947489

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