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Increased levels of HE4 (WFDC2) in systemic sclerosis: a novel biomarker reflecting interstitial lung disease severity?

BACKGROUND: Human epididymis protein 4 (HE4, also known as WFDC-2) has been implicated in fibrotic disorders pathobiology. We tested the hypothesis that HE4 may be used as a candidate biomarker for systemic sclerosis (SSc)-related interstitial lung disease (SSc-ILD). METHODS: A total of 169 consecut...

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Detalles Bibliográficos
Autores principales: Zhang, Mingxia, Zhang, Liyun, E, Linning, Xu, Ke, Wang, Xu Fei, Zhang, Bin, Su, Jie, Meng, Zemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488885/
https://www.ncbi.nlm.nih.gov/pubmed/32963750
http://dx.doi.org/10.1177/2040622320956420