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Identification of miPEP133 as a novel tumor-suppressor microprotein encoded by miR-34a pri-miRNA

BACKGROUND: Very few proteins encoded by the presumed non-coding RNA transcripts have been identified. Their cellular functions remain largely unknown. This study identifies the tumor-suppressor function of a novel microprotein encoded by the precursor of miR-34a. It consists of 133 amino acid resid...

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Detalles Bibliográficos
Autores principales: Kang, Min, Tang, Bo, Li, Jixi, Zhou, Ziyan, Liu, Kang, Wang, Rensheng, Jiang, Ziyan, Bi, Fangfang, Patrick, David, Kim, Dongin, Mitra, Anirban K., Yang-Hartwich, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489042/
https://www.ncbi.nlm.nih.gov/pubmed/32928232
http://dx.doi.org/10.1186/s12943-020-01248-9