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Assessment of Doxorubicin and Pembrolizumab in Patients With Advanced Anthracycline-Naive Sarcoma: A Phase 1/2 Nonrandomized Clinical Trial

IMPORTANCE: Anthracycline-based therapy is standard first-line treatment for most patients with advanced and metastatic sarcomas. Although multiple trials have attempted to show improved outcomes in patients with soft-tissue sarcoma over doxorubicin monotherapy, each has fallen short of demonstratin...

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Detalles Bibliográficos
Autores principales: Pollack, Seth M., Redman, Mary W., Baker, Kelsey K., Wagner, Michael J., Schroeder, Brett A., Loggers, Elizabeth T., Trieselmann, Kathryn, Copeland, Vanessa C., Zhang, Shihong, Black, Graeme, McDonnell, Sabrina, Gregory, Jeffrey, Johnson, Rylee, Moore, Roxanne, Jones, Robin L., Cranmer, Lee D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489365/
https://www.ncbi.nlm.nih.gov/pubmed/32910151
http://dx.doi.org/10.1001/jamaoncol.2020.3689