Human esophageal myofibroblasts increase squamous epithelial thickness via paracrine mechanisms in an in vitro model of gastroesophageal reflux disease

The pathogenesis of esophageal injury in gastroesophageal reflux disease (GERD) is incompletely understood. We modeled exposure of human esophageal myofibroblasts (HEMFs) to gastroesophageal reflux by repeated treatment with pH 4.5 and pH 4.5 bile salts and determined the effects on the epithelium i...

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Detalles Bibliográficos
Autores principales: Hu, Liping, Zhang, Chunying, Yang, Kevin, Li, Meng, Shaker, Anisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489504/
https://www.ncbi.nlm.nih.gov/pubmed/32925965
http://dx.doi.org/10.1371/journal.pone.0238852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489504/
https://www.ncbi.nlm.nih.gov/pubmed/32925965
http://dx.doi.org/10.1371/journal.pone.0238852

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