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Treatment-related adverse events as surrogate to response rate to immune checkpoint blockade

BACKGROUND: Immune checkpoint blockade (ICB) brings hope to many late-stage cancer patients yet its marker for response remains elusive. METHODS: We developed a hypothesis that treatment-related adverse events (TrAEs) could predict objective response rate (ORR) to ICB. We plotted ORR against corresp...

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Detalles Bibliográficos
Autores principales: Shen, Yanyun, Chen, Yunfeng, Wang, Duoqin, Zhu, Zhidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489750/
https://www.ncbi.nlm.nih.gov/pubmed/32925773
http://dx.doi.org/10.1097/MD.0000000000022153