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Miro, a Rho GTPase genetically interacts with Alzheimer's disease-associated genes (Tau, Aβ(42) and Appl) in Drosophila melanogaster

Miro (mitochondrial Rho GTPases), a mitochondrial outer membrane protein, facilitates mitochondrial axonal transport along the microtubules to facilitate neuronal function. It plays an important role in regulating mitochondrial dynamics (fusion and fission) and cellular energy generation. Thus, Miro...

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Detalles Bibliográficos
Autores principales: Panchal, Komal, Tiwari, Anand Krishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489762/
https://www.ncbi.nlm.nih.gov/pubmed/32747449
http://dx.doi.org/10.1242/bio.049569