A small molecule inhibitor of HER3: a proof-of-concept study

Despite being catalytically defective, pseudokinases are typically essential players of cellular signalling, acting as allosteric regulators of their active counterparts. Deregulation of a growing number of pseudokinases has been linked to human diseases, making pseudokinases therapeutic targets of...

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Detalles Bibliográficos
Autores principales: Colomba, Audrey, Fitzek, Martina, George, Roger, Weitsman, Gregory, Roberts, Selene, Zanetti-Domingues, Laura, Hirsch, Michael, Rolfe, Daniel J., Mehmood, Shahid, Madin, Andrew, Claus, Jeroen, Kjaer, Svend, Snijders, Ambrosius P., Ng, Tony, Martin-Fernandez, Marisa, Smith, David M., Parker, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489893/
https://www.ncbi.nlm.nih.gov/pubmed/32815546
http://dx.doi.org/10.1042/BCJ20200496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489893/
https://www.ncbi.nlm.nih.gov/pubmed/32815546
http://dx.doi.org/10.1042/BCJ20200496

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