Quantitative propagation of assembled human Tau from Alzheimer's disease brain in microfluidic neuronal cultures

Tau aggregation and hyperphosphorylation is a key neuropathological hallmark of Alzheimer's disease (AD), and the temporospatial spread of Tau observed during clinical manifestation suggests that Tau pathology may spread along the axonal network and propagate between synaptically connected neur...

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Detalles Bibliográficos
Autores principales: Katsikoudi, Antigoni, Ficulle, Elena, Cavallini, Annalisa, Sharman, Gary, Guyot, Amelie, Zagnoni, Michele, Eastwood, Brian J., Hutton, Michael, Bose, Suchira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Neurobiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489902/
https://www.ncbi.nlm.nih.gov/pubmed/32699110
http://dx.doi.org/10.1074/jbc.RA120.013325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489902/
https://www.ncbi.nlm.nih.gov/pubmed/32699110
http://dx.doi.org/10.1074/jbc.RA120.013325

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