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Structural and functional studies of Arabidopsis thaliana legumain beta reveal isoform specific mechanisms of activation and substrate recognition

The vacuolar cysteine protease legumain plays important functions in seed maturation and plant programmed cell death. Because of their dual protease and ligase activity, plant legumains have become of particular biotechnological interest, e.g. for the synthesis of cyclic peptides for drug design or...

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Detalles Bibliográficos
Autores principales: Dall, Elfriede, Zauner, Florian B., Soh, Wai Tuck, Demir, Fatih, Dahms, Sven O., Cabrele, Chiara, Huesgen, Pitter F., Brandstetter, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489914/
https://www.ncbi.nlm.nih.gov/pubmed/32719006
http://dx.doi.org/10.1074/jbc.RA120.014478