TAT-Modified Gold Nanoparticles Enhance the Antitumor Activity of PAD4 Inhibitors

PURPOSE: Histone citrullination by peptidylarginine deiminases 4 (PAD4) regulates the gene expression of tumor suppressor. In our previously study, YW3-56 (356) was developed as a potent PAD4 inhibitor for cancer therapy with novel function in the autophagy pathway. To enhance the antitumor activity...

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Detalles Bibliográficos
Autores principales: Song, Songlin, Gui, Lin, Feng, Qiqi, Taledaohan, Ayijiang, Li, Yuanming, Wang, Wei, Wang, Yanming, Wang, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490092/
https://www.ncbi.nlm.nih.gov/pubmed/32982225
http://dx.doi.org/10.2147/IJN.S255546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490092/
https://www.ncbi.nlm.nih.gov/pubmed/32982225
http://dx.doi.org/10.2147/IJN.S255546

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