S100A4 Silencing Facilitates Corneal Wound Healing After Alkali Burns by Promoting Autophagy via Blocking the PI3K/Akt/mTOR Signaling Pathway

PURPOSE: This study investigated the role of S100 calcium binding protein A4 (S100A4) in corneal wound healing and the underlying mechanism of the S100A4-mediated PI3K/Akt/mammalian target of rapamycin (mTOR) pathway. METHODS: The rabbit corneal alkali burn model was established in vivo. S100A4 expr...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yulin, Gao, Guiping, Wu, Ying, Wang, Yuqin, Wu, Xiaorong, Zhou, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490227/
https://www.ncbi.nlm.nih.gov/pubmed/32926102
http://dx.doi.org/10.1167/iovs.61.11.19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490227/
https://www.ncbi.nlm.nih.gov/pubmed/32926102
http://dx.doi.org/10.1167/iovs.61.11.19

Ejemplares similares