Cargando…

S100A4 Silencing Facilitates Corneal Wound Healing After Alkali Burns by Promoting Autophagy via Blocking the PI3K/Akt/mTOR Signaling Pathway

PURPOSE: This study investigated the role of S100 calcium binding protein A4 (S100A4) in corneal wound healing and the underlying mechanism of the S100A4-mediated PI3K/Akt/mammalian target of rapamycin (mTOR) pathway. METHODS: The rabbit corneal alkali burn model was established in vivo. S100A4 expr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yulin, Gao, Guiping, Wu, Ying, Wang, Yuqin, Wu, Xiaorong, Zhou, Qiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2020
Materias:	Cornea
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490227/ https://www.ncbi.nlm.nih.gov/pubmed/32926102 http://dx.doi.org/10.1167/iovs.61.11.19

Ejemplares similares

Subconjunctival Injection of Regulatory T Cells Potentiates Corneal Healing Via Orchestrating Inflammation and Tissue Repair After Acute Alkali Burn
por: Yan, Dan, et al.
Publicado: (2020)

Forkhead Domain Inhibitor-6 Suppresses Corneal Neovascularization and Subsequent Fibrosis After Alkali Burn in Rats
por: Lan, Chunlin, et al.
Publicado: (2022)

Epigenetic Landscape Analysis of the Long Non-Coding RNA and Messenger RNA in a Mouse Model of Corneal Alkali Burns
por: Jiang, Li, et al.
Publicado: (2021)

Wound Healing After Alkali Burn Injury of the Cornea Involves Nox4-Type NADPH Oxidase
por: Hakami, Nora Y., et al.
Publicado: (2020)

Erratum in: S100A4 Silencing Facilitates Corneal Wound Healing After Alkali Burns by Promoting Autophagy via Blocking the PI3K/Akt/mTOR Signaling Pathway
Publicado: (2021)

Sustained Subconjunctival Delivery of Infliximab Protects the Cornea and Retina Following Alkali Burn to the Eye
por: Zhou, Chengxin, et al.
Publicado: (2017)

Dioleoylphosphatidylglycerol Accelerates Corneal Epithelial Wound Healing
por: Bollag, Wendy B., et al.
Publicado: (2020)

Effect of Human Corneal Mesenchymal Stromal Cell-derived Exosomes on Corneal Epithelial Wound Healing
por: Samaeekia, Ravand, et al.
Publicado: (2018)

Proteome Composition of Bovine Amniotic Membrane and Its Potential Role in Corneal Healing
por: Capistrano da Silva, Erotides, et al.
Publicado: (2021)

Effect of TRPM8 Functional Loss on Corneal Epithelial Wound Healing in Mice
por: Ran, Lili, et al.
Publicado: (2023)

dsRNA Induced IFNβ-MMP13 Axis Drives Corneal Wound Healing
por: Lan, Xihong, et al.
Publicado: (2022)

Topical Losartan and Corticosteroid Additively Inhibit Corneal Stromal Myofibroblast Generation and Scarring Fibrosis After Alkali Burn Injury
por: Sampaio, Lycia Pedral, et al.
Publicado: (2022)

PTEN Inhibition Accelerates Corneal Endothelial Wound Healing through Increased Endothelial Cell Division and Migration
por: Zhang, Weijie, et al.
Publicado: (2020)

Advanced Glycation End Products and Receptor (RAGE) Promote Wound Healing of Human Corneal Epithelial Cells
por: Gross, Christelle, et al.
Publicado: (2020)

Corneal Sensitivity and Tear Function in Recurrent Corneal Erosion Syndrome
por: Kang, Eugene Yu-Chuan, et al.
Publicado: (2020)

Agrin Promotes Limbal Stem Cell Proliferation and Corneal Wound Healing Through Hippo-Yap Signaling Pathway
por: Hou, Lulu, et al.
Publicado: (2020)

PEDF Gene Deletion Disrupts Corneal Innervation and Ocular Surface Function
por: Shang, Zhenying, et al.
Publicado: (2021)

Role of the Neurokinin-1 Receptor in the Promotion of Corneal Epithelial Wound Healing by the Peptides FGLM-NH(2) and SSSR in Neurotrophic Keratopathy
por: Yanai, Ryoji, et al.
Publicado: (2020)

Corneal Hydration Control in Fuchs' Endothelial Corneal Dystrophy
por: Wacker, Katrin, et al.
Publicado: (2016)

The Role of the miR-21/SPRY2 Axis in Modulating Proangiogenic Factors, Epithelial Phenotypes, and Wound Healing in Corneal Epithelial Cells
por: Zhang, Yun, et al.
Publicado: (2019)

The NLRP3 Activation in Infiltrating Macrophages Contributes to Corneal Fibrosis by Inducing TGF-β1 Expression in the Corneal Epithelium
por: Xu, Jing, et al.
Publicado: (2022)

The Wound Healing Effect of Doxycycline after Corneal Alkali Burn in Rats
por: Yi, Qiong, et al.
Publicado: (2019)

Administration of Menadione, Vitamin K3, Ameliorates Off-Target Effects on Corneal Epithelial Wound Healing Due to Receptor Tyrosine Kinase Inhibition
por: Rush, Jamie S., et al.
Publicado: (2016)

Sympathetic Nerves Coordinate Corneal Epithelial Wound Healing by Controlling the Mobilization of Ly6C(hi) Monocytes From the Spleen to the Injured Cornea
por: He, Siyu, et al.
Publicado: (2023)

Inhibitory effects of S100A4 gene silencing on alkali burn-induced corneal neovascularization: an in vivo study
por: Wang, Yu-Lin, et al.
Publicado: (2017)

Myh11 Lineage Corneal Endothelial Cells and ASCs Populate Corneal Endothelium
por: Corliss, Bruce A., et al.
Publicado: (2019)

Topical Pergolide Enhance Corneal Nerve Regrowth Following Induced Corneal Abrasion
por: Zhang, Xiaohui, et al.
Publicado: (2020)

Long Noncoding RNA 3632454L22Rik Contributes to Corneal Epithelial Wound Healing by Sponging miR-181a-5p in Diabetic Mice
por: Chen, Xiaxue, et al.
Publicado: (2021)

Vitamin D Induces Global Gene Transcription in Human Corneal Epithelial Cells: Implications for Corneal Inflammation
por: Reins, Rose Y., et al.
Publicado: (2016)

Corneal Keratocyte Density and Corneal Nerves Are Reduced in Patients With Severe Obesity and Improve After Bariatric Surgery
por: Iqbal, Zohaib, et al.
Publicado: (2021)

Polysaccharide Hydrogel Combined with Mesenchymal Stem Cells Promotes the Healing of Corneal Alkali Burn in Rats
por: Ke, Yifeng, et al.
Publicado: (2015)

Inhibition of Human Corneal Myofibroblast Formation
por: Guo, Xiaoqing, et al.
Publicado: (2018)

The Corneal Epithelial Barrier and Its Developmental Role in Isolating Corneal Epithelial and Conjunctival Cells From One Another
por: Kubilus, James K., et al.
Publicado: (2017)

Inducible Slc4a11 Knockout Triggers Corneal Edema Through Perturbation of Corneal Endothelial Pump
por: Ogando, Diego G., et al.
Publicado: (2021)

Effects of Corneal Hydration on Brillouin Microscopy In Vivo
por: Shao, Peng, et al.
Publicado: (2018)

Descemet's Membrane Modulation of Posterior Corneal Fibrosis
por: Medeiros, Carla S., et al.
Publicado: (2019)

Transcriptomic Profiling of Posterior Polymorphous Corneal Dystrophy
por: Chung, Doug D., et al.
Publicado: (2017)

Examination of the effects of COVID 19 on corneal endothelium
por: Erdem, Seyfettin, et al.
Publicado: (2021)

Automated vs. human evaluation of corneal staining
por: Kourukmas, R., et al.
Publicado: (2022)

Ambient Air Currents Activate Corneal Nerves During Ocular Desiccation in Rats: Simultaneous Recordings of Neural Activity and Corneal Temperature
por: Hirata, Harumitsu, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_rnnl8aq6rarl9qv3db0d3j0rts